上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (8): 1086-.doi: 10.3969/j.issn.1674-8115.2011.08.008

• 专题报道（眼科视觉科学） • 上一篇    下一篇

新型角膜地形图仪观察泪膜稳定性及其与眼表角膜温度的关系

沈 婷, 张 琳   

  1. 上海交通大学 医学院附属仁济医院眼科, 上海 200001
  • 出版日期:2011-08-28 发布日期:2011-08-29
  • 通讯作者: 张 琳, 电子信箱: linlinrj172@hotmail.com。
  • 作者简介:沈 婷(1986—), 女, 硕士生；电子信箱: cindy710@126.com。
  • 基金资助:

    上海市浦东新区社会发展局卫生科技基金(PW2008D-2)

Relationship between temperature of cornea on ocular surface and stability of tear film determined by new corneal topography

SHEN Ting, ZHANG Lin   

  1. Department of Ophthalmology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China
  • Online:2011-08-28 Published:2011-08-29
  • Supported by:

    Shanghai Pudong New Area Social Development Bureau Foundation, PW2008D-2

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摘要：

目的 探讨眼表角膜温度与泪膜稳定性的关系。方法 选取泪液分泌试验(SchirmerⅠ)结果>10 mm/5 min的94例患者，根据干眼症状和泪膜破裂时间（BUT）检查结果分为干眼组（n=48）和非干眼组（n=46）。新型角膜地形图仪拍摄泪膜分布图像，红外线温度计测量眼表角膜温度，分析泪膜稳定性与BUT和眼表角膜温度的关系。结果 干眼组泪膜稳定性分级显著高于非干眼组（P<0.01）。泪膜稳定性分级与BUT呈显著负相关(r=-0.752，P=0.00)。根据泪膜稳定性分级，0级、Ⅰ级、Ⅱ级和Ⅲ级患者的平均眼表角膜温度分别为(32.386±0.826 2) ℃、(34.084±1.373 3) ℃、(34.980±1.331 5)℃和(35.709±0.744 9) ℃，各级患者眼表角膜温度差异均有统计学意义（均P<0.01）。结论 新型角膜地形图仪可反映泪膜的稳定性。眼表角膜温度升高，泪膜稳定性减弱，可能是造成蒸发过强型干眼的因素之一。

关键词: 眼表角膜温度, 泪膜稳定性, 新型角膜地形图仪, 蒸发过强型干眼

Abstract:

Objective To explore the relationship between temperature of cornea on ocular surface and stability of tear film. Methods A total of 94 patients with results of SchirmerⅠ test >10 mm/5 min were enrolled, and were divided into dry eye group （n=48）and non-dry eye group （n=46）based on dry eye complaints and results of break up time (BUT) test. New corneal topography was adopted to take the division photos of tear film, and infrared thermometer was used to measure temperature of cornea on ocular surface. The relationship between the stability of tear film and temperature of cornea on ocular surface was analysed. Results The grades of tear film images in dry eye group were significantly higher than those in non-dry eye group (P<0.01). The grades of tear film images were negatively correlated with BUT results (r=－0.752，P=0.00). By grades of tear film images, the average temperature of cornea on ocular surface of grade 0, gradeⅠ, grade Ⅱ and grade Ⅲ was (32.386±0.826 2) ℃, (34.084±1.373 3) ℃, (34.980±1.331 5) ℃ and (35.709±0.744 9) ℃ respectively, with significant differences among all grades （P<0.01）. Conclusion New corneal topography can reveal the stability of tear film. Higher temperature of cornea on ocular surface may cause instability of tear film, which is one of the major causes for dry eye.

Key words: temperature of cornea on ocular surface, stability of tear film, new corneal topography, evaporative dry eye