上海交通大学学报(医学版)

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美沙酮维持治疗门诊患者丙型肝炎病毒感染情况及求治动机评估

张蕾1, 李质彬2, 韩慧1, 杜江1, 赵敏1   

  1. 1.上海交通大学 医学院附属精神卫生中心物质依赖与成瘾科,上海 200030;2.上海市嘉定区精神卫生中心,上海 201806
  • 出版日期:2016-09-28 发布日期:2016-10-31
  • 通讯作者: 杜江, 电子信箱: dujiangdou@163.com。 赵敏, 电子信箱: drminzhao@gmail.com。
  • 作者简介:张蕾(1991—), 女, 硕士生; 电子信箱: 403474162@qq.com。
  • 基金资助:

    国家临床重点专科-上海市精神卫生中心(OMA-MH 2011-873);上海市教育委员会高峰高原学科建设计划(20152235)

Evaluation of hepatitis C virus infection and treatment motivation among patients receiving methadone maintenance treatment

ZHANG Lei1, LI Zhi-bin2, HAN Hui1, DU Jiang1, ZHAO Min1   

  1. 1.Department of Substance Abuse and Addiction, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China; 2.Shanghai Jiading Mental Health Center, Shanghai 201806, China
  • Online:2016-09-28 Published:2016-10-31
  • Supported by:

    National Key Clinical Disciplines at Shanghai Mental Health Center, OMA-MH 2011-873; Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support,20152235

摘要:

目的·调查上海市美沙酮维持治疗门诊海洛因依赖者丙型肝炎病毒(HCV)感染情况、丙型肝炎相关知识水平,以及求治动机等,为今后制订相关干预策略提供依据。方法·对240名参加美沙酮维持治疗的患者进行血清学检查,了解HCV感染情况。采用丙型肝炎相关知识调查问卷、酒精使用障碍筛查问卷、病耻感问卷、Beck抑郁自评量表、Beck焦虑自评量表,对患者进行相关评估。结果·调查对象HCV感染率为70.0%(168/240),且多数合并甲型肝炎病毒感染(43.3%);丙型肝炎相关知识评估得分较低,平均得分为6.5±3.5,缺乏自我保护意识;影响患者治疗动机的主要因素是治疗费用。结论·上海地区美沙酮维持治疗门诊患者HCV感染率较高,且相关知识缺乏,影响患者求治动机的因素复杂。

关键词: 美沙酮维持治疗, 丙型肝炎, 海洛因依赖者

Abstract:

Objective·To investigate the hepatitis C virus (HCV) infection, knowledge related to hepatitis C virus, and treatment motivation among the heroin dependents treated in methadone maintenance treatment (MMT) clinics and to provide evidence for formulating related intervention strategies in the future. Methods·Two hundred and forty participants receiving MMT underwent serologic test to evaluate HCV infection among them. HCV related knowledge questionnaire, AUDIT, Stigma Scale, Beck Depression Inventory, and Beck Anxiety Inventory were used to assess patients. Results·The HCV infection rate among participants was 70.0% (168/240) and most of them were co-infected with hepatitis A (43.3%). HCV knowledge scores were low due to lack of self-protection consciousness and average scores were 6.5±3.5. The main factor affecting the motivation to treatment is treatment costs. Conclusion·The HCV infection rate in MMT patients is high and the patients lack related knowledge. The factors influencing the motivation for treatment are complicated.

Key words: methadone maintenance treatment, hepatitis C virus, heroin dependent