上海交通大学学报（医学版）

上海交通大学学报（医学版）

• 病例报告 • 上一篇    下一篇

肝原发性腺鳞癌5例临床病理观察

龙满美，贺薇，何巧，施永恒，刘强   

  1. 上海交通大学 医学院附属仁济医院病理科，上海 200127
  • 出版日期:2017-02-28 发布日期:2017-02-28
  • 通讯作者: 刘强，电子信箱：liuq1963@sohu.com。
  • 作者简介:龙满美（1989—），女，住院医师，硕士；电子信箱：longmanmei1989@163.com。

Clinicopathological observation of 5 cases of primary liver adenosquamous carcinoma

LONG Man-mei, HE Wei, HE Qiao, SHI Yong-heng, LIU Qiang   

  1. Department of Pathology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
  • Online:2017-02-28 Published:2017-02-28

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摘要：

肝原发性腺鳞癌是一种十分罕见的肝脏恶性肿瘤，预后极差。该文回顾性分析了5例肝原发性腺鳞癌患者的临床资料，其中男性4例，女性1例，年龄50～67岁，平均年龄60.2岁。组织学特点为腺癌和鳞癌2种成分混合存在，5例均以鳞癌成分为主且比例超过80%。4例采用手术切除，1例进行肝移植；术后随访6～35个月，中位生存时间15个月。截至随访日期死亡3例，存活2例，术后1年和2年生存率分别为60%和20%。

关键词: 肝原发性腺鳞癌, 诊断, 预后

Abstract:

Primary liver adenosquamous carcinoma is a rare kind of liver malignant tumor with very poor prognosis. Clinical data of 5 cases were analyzed retrospectively, four male and one female, whose average age was 60.2 years (50-67 years) old. Adenosquamous carcinoma contains both adenocarcinoma and squamous carcinoma histologically, and squamous carcinoma cells are dominant (>80%). Four cases underwent surgical resection and one received liver transplantation. The postoperative follow-up period ranged from 6 to 35 months and the mean survival time of these cases was about 15 months. Three patients died during the follow-up period. The survival rates 1 and 2 years after operation were 60% and 20%, respectively.

Key words: primary liver adenosquamous carcinoma, diagnosis, prognosis