上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2017, Vol. 37 ›› Issue (9): 1207-.doi: 10.3969/j.issn.1674-8115.2017.09.004

• 论著（基础研究） • 上一篇    下一篇

上海市静安区12月龄婴儿丹佛发育筛查及其智能发育相关因素分析#br#

石惠卿 1，王红兵 2，陈津津 1   

  1. 1. 上海交通大学附属儿童医院儿童保健科，上海 200026；2. 上海第四康复医院儿童保健科，上海 200041
  • 出版日期:2017-09-28 发布日期:2017-10-10
  • 通讯作者: 陈津津，电子信箱：jjvoo@163.com
  • 作者简介:石惠卿（1991—），女，硕士生；电子信箱：rukawayouko@163.com
  • 基金资助:
     国家自然科学基金（81670810）；上海市科学技术委员会医学引导类项目（14411965200）；上海申康医院发展中心临床科技创新项目（SHDC12015305）； 上海市教育委员会高峰高原学科建设计划（20161432）；上海市儿童健康服务能力建设专项规划高端儿科海外研修团队培养计划（GDEK201710）；上海申康医 院发展中心常见疾病适宜技术研发与推广应用项目（16CR4018A）

Survey on infants aged 12 months in Shanghai Jing'an District by Denver Development Screening Test and analysis of their intellectual development relevant risk factors#br#

SHI Hui-qing1, WANG Hong-bing2, CHEN Jin-jin1   

  1. 1. Department of Children Healthcare, Shanghai Children Hospital, Shanghai Jiao Tong University, Shanghai 200026, China; 2. Department of Children Healthcare, The Fourth Rehabilitation Hospital , Shanghai 200041, China
  • Online:2017-09-28 Published:2017-10-10
  • Supported by:
    National Natural Science Foundation of China, 81670810; Science and Technology Commission of Shanghai Municipality Medical Guiding Project, 14411965200; Shanghai Hospital Development Center Clinical Research Innovation Project, SHDC12015305; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support, 20161432; Shanghai Children's Health Services Capacity Planning Special Program for Advanced Pediatric Overseas Research Team Training Program, GDEK201710; Shanghai Hospital Development Center Suitable Technology Research and Development for Common Diseases, 16CR4018A

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摘要： 目的 · 了解社区儿童早期发育情况并探究影响婴幼儿发育的危险因素。方法 · 采用整群抽样的方法，对上海市静安区常住 12 月龄儿童行丹佛发育量表筛查。运用Logistic 回归分析探究儿童智能发育影响因素。结果 · 该调查共收集样本4 102 例，抽检异 常率为1.0%，可疑异常率为4.3%。Logistic 回归分析结果显示低出生体质量（OR=6.24, 95% CI 1.69 ～ 22.98，P=0.006)、头围偏小 （OR=5.22，95% CI 1.20 ～ 22.84，P=0.031)、母亲高龄（OR=3.61，95% CI 1.32 ～ 9.84，P=0.012)、存在脑损伤史（OR=3.96，95% CI 1.55 ～ 10.10，P=0.003) 是筛查出现异常结果的危险因素。Spearman 秩相关分析显示，母乳喂养时长（0 ～ 12 月）与筛查可疑异常结 果呈负相关（ρ=-0.031，P=0.046）。 结论 · 应重视婴儿早期发育筛查和干预，特别是针对母亲为高龄产妇、非正常出生体质量、头围 偏小及存在产前或新生儿期高危因素的儿童。母乳喂养有助于降低发育不良结果的检出率。

关键词: 丹佛发育筛查测试, 危险因素, 母乳喂养, 婴幼儿

Abstract:

 Objective · To investigate the developmental state of infants in early childhood and identify risk factors for their early development in community.  Methods · Cluster sampling was conducted to collect data of infants aged 12 months by Denver Developmental Screening Test (DDST) in Shanghai Jing’an District. Logistic analysis was employed to detect factors influencing the intellectual development of infants.  Results · A total of 4 102 infants were enrolled in the survey. The prevalence for abnormal screening result was 1.0%, while 4.3% for suspicious abnormal result. Logistic analysis revealed that low birth weight (OR=6.24, 95% CI 1.69-22.98, P=0.006), low head circumference (OR=5.22, 95% CI 1.20-22.84, P=0.031), mothers older than 35 years in pregnancy (OR=3.61, 95%CI 1.32-9.84, P=0.012) or history of brain impairment (OR=3.96, 95% CI 1.55-10.10, P=0.003) were the risk factors for abnormal screening result. Spearman rank correlation analysis showed a significant negative relationship between breastfeeding duration and suspicious abnormal screening result (ρ=-0.031, P=0.046).  Conclusion · It is essential to draw attention to early developmental screening and interference, especially to infants with mothers older than 35 years in pregnancy, low birth weight, low head circumference or high-risk infants. Breastfeeding is helpful for decreasing detection rate of abnormal result.

Key words: Denver Developmental Screening Test, risk factor, breastfeeding, infants