上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2018, Vol. 38 ›› Issue (12): 1504-.doi: 10.3969/j.issn.1674-8115.2018.12.020

• 专栏·转化医学 • 上一篇    

全球精准医疗研究的热点分析

刘洁，吴慧，仇晓春   

  1. 上海交通大学医学院图书馆，上海 200025
  • 出版日期:2018-12-28 发布日期:2019-01-27
  • 通讯作者: 仇晓春，电子信箱：tsg2@shsmu.edu.cn。
  • 作者简介:刘洁（1986—）女，馆员，硕士；电子信箱： liujie@shsmu.edu.cn。
  • 基金资助:
    上海市 2017年度“科技创新行动计划”软科学研究重点项目（ 17692110300）

Research hotspots of precision medicine

LIU Jie, WU Hui, QIU Xiao-chun   

  1. Library of Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Online:2018-12-28 Published:2019-01-27
  • Supported by:
    Soft Science Research Key Project of Shanghai 2017 “Science and Technology Innovation Action Plan”, 17692110300

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摘要： 目的 ·分析精准医疗领域的研究现状，客观反映相关国家的科研能力，揭示精准医疗的研究热点。方法 ·以 PubMed为检索对象，检索 2013— 2017年全球有关 “精准医疗”方面的文献，采用文献计量学方法，分析精准医疗研究相关文献的发文量、国家 /地区分布、期刊分布、高被引论文、研究热点等几方面现状。结果 ·在 PubMed数据库中检索得到 23 284条结果，共词主要集中于“分子靶向治疗”和“抗肿瘤药物”等方面。结论 ·肿瘤分子靶向治疗是精准医疗领域的研究热点和发展趋势，抗肿瘤药物的研究是分子靶向治疗的主要关注内容。

关键词: 精准医疗, 个性化医疗, 文献计量分析, 共词分析, 热点分析

Abstract:

Objective · To give a retrospective bibliometric analysis of documents about precision medicine and to reveal the characteristics and hotspots of global research output. Methods · Articles about the research of precision medicine between 2013 and 2017 were retrieved in PubMed and bibliometric methods were used to evaluate global scientific output and to identify the most active factors, such as countries, journals, highly cited papers, etc. Coword analysis was also used to show the research hotspots and trends. Results · A total of 23 284 publications on the research of precision medicine 2013 to 2017 were retrieved in this study. “Molecular targeted therapy” and “antineoplastic agents” were the most frequently used co-words in precision medicine. Conclusion · Molecular targeted therapy for cancer treatment is the hotspot in the precision medicine research, in which the study of antineoplastic agents is the main topic.

Key words: precision medicine, personalized medicine, bibliometric analysis, co-word analysis, hotspots analysis

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