上海交通大学学报(医学版) ›› 2019, Vol. 39 ›› Issue (2): 203-.doi: 10.3969/j.issn.1674-8115.2019.02.018

• 综述 • 上一篇    下一篇

补骨脂素的植物雌激素样作用研究进展

李虎虓,宋忠臣   

  1. 上海交通大学医学院附属精神卫生中心,上海 200030
  • 出版日期:2019-02-28 发布日期:2019-03-19
  • 通讯作者: 宋忠臣,电子信箱:szhongchen@sina.com。
  • 作者简介:李虎虓(1994—),男,硕士生;电子信箱: tentigerli@163.com。
  • 基金资助:
    国家重点研发计划(2017YFC0840100,2017YFC0840110)

Advance in phytoestrogenic effects of psoralen

LI Hu-xiao, SONG Zhong-chen   

  1. Department of Periodontology, Shanghai Ninth Peoples Hospital, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai 200011, China
  • Online:2019-02-28 Published:2019-03-19
  • Supported by:
    National Key Research and Development Program of China, 2017YFC0840100, 2017YFC0840110)。

摘要: 补骨脂素是自中药补骨脂中提取的有效活性成分之一。研究发现补骨脂素具有雌激素样作用,能对雌激素受体起到一定调节作用。补骨脂素可以发挥抗肿瘤、抗骨质疏松、抗氧化和保护心血管等植物雌激素样作用。该文就补骨脂素的植物雌激素样作用研究进展作一综述。

关键词: 补骨脂素, 雌激素, 植物雌激素, 雌激素受体

Abstract: Psoralen is one of the effective ingredients extracted Chinese herbal medicine Psoralea corylifolia. Studies have found that psoralen has an estrogenic effect and can regulate the estrogen receptor. Psoralen can exert phytoestrogenic effects such as anti-tumor, anti-osteoporosis, anti-oxidation and protection of cardiovascular. This article reviewed the research progress of phytoestrogenic effects of psoralen.

Key words: psoralen, estrogen, phytoestrogens, estrogen receptor

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