上海交通大学学报（医学版）

›› 2010, Vol. 30 ›› Issue (4): 474-.

• 综述 • 上一篇    下一篇

病毒microRNA研究进展

曹国君, 综述；孙佳彬, 季育华, 审校   

  1. 上海交通大学 医学院瑞金医院检验科, 上海 200025
  • 出版日期:2010-04-25 发布日期:2010-04-26
  • 通讯作者: 季育华, 电子信箱: rjjyh@yahoo.com.cn。
  • 作者简介:曹国君（1984—）, 男, 硕士生；电子信箱: gjcao@foxmail.com。
  • 基金资助:

    上海市科委重大基础研究项目（074119521）

Research progress of viral microRNA

CAO Guo-jun, reviewer；SUN Jia-bin, JI Yu-hua, reviser   

  1. Department of Clinical Laboratory, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China
  • Online:2010-04-25 Published:2010-04-26
  • Supported by:

    Major Fundamental Research Program of Shanghai Science and Technology Committee, 074119521

PDF (PC)

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摘要：

microRNA（miRNA)是一种含有约22个核苷酸的RNA分子，它可以介导基因表达的转录后调节，可调节细胞的生长、分化、凋亡、细胞周期和免疫反应等。已逐步发现多种病毒miRNA，该文就近年来病毒miRNA的研究进展作一综述。

关键词: 病毒, microRNA, 基因表达, 调控

Abstract:

microRNA (miRNA) has approximately 22 nucleotides that can mediate the posttranscriptional regulation of gene expression. miRNA can regulate cellular processes such as development, differentiation, cell cycling, apoptosis and immune responses. More and more viral miRNA has been unveiled. The research progress of viral miRNA is reviewed in this paper.

Key words: virus, microRNA, gene expression, regulation