›› 2010, Vol. 30 ›› Issue (6): 628-.

• 专题报道(抑郁障碍研究) • 上一篇    下一篇

早年创伤与抑郁症及抑郁症患者自杀倾向的相关性分析

苑成梅, 黄 佳, 王 振, 李则挚, 王志阳, 易正辉, 王 勇, 洪 武, 彭代辉, 陈 俊, 胡莺燕, 曹 岚, 方贻儒   

  1. 上海交通大学 医学院附属精神卫生中心心境障碍科, 上海 200030
  • 出版日期:2010-06-25 发布日期:2010-06-28
  • 通讯作者: 方贻儒, 电子信箱: yirufang@yahoo.com.cn。
  • 作者简介:苑成梅(1975—), 女, 主治医师, 博士生;电子信箱: yuanchengmei@hotmail.com。
  • 基金资助:

    上海市卫生局公共卫生优秀青年人才项目(08GWQ075);上海市卫生局青年科研项目(2007Y14);国家高技术研究发展计划(“863”计划)(2006AA02Z430);“十五”国家科技攻关计划(2004BA720A21-02)

Correlation analysis of early trauma experience and depression and suicidal tendency of patients with depression

YUAN Cheng-mei, HUANG Jia, WANG Zhen, LI Ze-zhi, WANG Zhi-yang, YI Zheng-hui, WANG Yong, HONG Wu, PENG Dai-hui, CHEN Jun, HU Ying-yan, CAO Lan, FANG Yi-ru   

  1. Division of Mood Disorder, Shanghai Mental Health Center, School of Medicine, Shanghai Jiaotong University, Shanghai 200030, China
  • Online:2010-06-25 Published:2010-06-28
  • Supported by:

    Shanghai Municipal Health Bureau Foundation, 08GWQ075, 2007Y14;Hi-Tech Research and Development Program of China, “863” Program, 2006AA02Z430;National Key Technologies R&D Program of “10th Five-year Plan”, 2004BA720A21-02

摘要:

目的 探讨早年创伤经历与抑郁症及抑郁症患者自杀倾向的相关性。方法 选取441例抑郁症患者(抑郁症组)和154正常对照(对照组),采用早年创伤问卷简表评估早年创伤情况,贝克抑郁自评问卷相关条目评估自杀倾向,运用MannWhitney非参数检验和Binary Logistic回归分析早年创伤与抑郁症及抑郁症患者自杀倾向的相关性。结果 抑郁症组与对照组情感虐待分量表分差异具有统计学意义(P<0.001);情感虐待分(β=0.410,P<0.001)和贝克抑郁自评问卷总分(β=0.134,P<0.001)进入最终的回归方程,方程的预测准确率为81.1%。结论 抑郁症患者有较多早年情感虐待经历;早年情感虐待经历与抑郁症患者自杀倾向密切相关,可能增加患者自杀的风险。

关键词: 早年创伤, 抑郁症, 自杀倾向

Abstract:

Objective To investigate the association between early trauma experience and depression and suicidal tendency of patients with depression. Methods Four hundred and forty-one patients with depression (depression group) and 154 healthy controls (control group) were enrolled. Early Trauma Inventory-Short Form was adopted to assess the early trauma experience, and Beck Depressive Inventory (BDI) was employed to evaluate the suicidal tendency of patients with depression. Mann-Whitney nonparametric test and Binary Logistic regression analysis were performed to explore the association between early trauma and depression and suicidal tendency of patients with depression. Results There was significant difference in the score of emotional abuse between depression group and control group (P<0.001). Score of emotional abuse (β=0.410,P<0.001) and total scores of BDI (β=0.134,P<0.001)were included in the ultimate regression equation, and the predictive efficiency of the equation was 81.1%. Conclusion Patients with depression have more early emotional abuse experience. Early emotional abuse experience is associated with suicidal tendency of patients with depression, and can increase the risk of suicide.

Key words: early trauma, depression, suicidal tendency