上海交通大学学报（医学版）

›› 2010, Vol. 30 ›› Issue (4): 471-.

• 综述 • 上一篇    下一篇

妊娠期心脏重构的研究进展

刘 华, 综述；林建华, 审校   

  1. 上海交通大学 医学院仁济医院妇产科 上海市产科心脏病监护中心, 上海 200127
  • 出版日期:2010-04-25 发布日期:2010-04-26
  • 通讯作者: 林建华, 电子信箱: linjhuarj@126.com。
  • 作者简介:刘 华(1978—), 女, 主治医师, 博士生；电子信箱: pterionsh@yahoo.com.cn。

Research development of cardiac remodeling in pregnancy

LIU Hua, reviewer；LIN Jian-hua, reviser   

  1. Department of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai Obstetric Cardiology Intensive Care Center, Shanghai 200127, China
  • Online:2010-04-25 Published:2010-04-26

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摘要：

妊娠期心脏重构主要表现为心脏肥大，是心脏适应妊娠期血流动力学变化的生理性改变，了解其发生机制对保障妊娠期母婴安全有极重要的意义。文章主要就妊娠期血流动力学变化、心脏变化及心脏重构的分子基础作一综述。

关键词: 妊娠, 心脏重构, 心脏肥大

Abstract:

Cardiac remodeling in pregnancy is mainly characterized by cardiac hypertrophy which is the physiological adaption of the heart to the hemodynamic changes in pregnancy. Understanding the mechanism is of great significance to ensure the maternal and fetal safety during pregnancy. This article reviews the main hemodynamic changes, cardiac changes and molecular mechanism of cardiac remodeling in pregnancy.

Key words: pregnancy, cardiac remodeling, cardiac hypertrophy