上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (6): 840-.doi: 10.3969/j.issn.1674-8115.2011.06.036

• 论著（预防医学） • 上一篇    下一篇

饮茶与卵巢癌患病风险相关的Meta分析

吴诗瑜1, 李妙竹2, 刘 延3, 韦明秀1   

  1. 1.上海交通大学 医学院附属瑞金医院卢湾分院妇科, 上海 200025； 2.中国科学院上海生命科学研究院营养科学研究所, 上海 200031； 3.上海交通大学 医学院附属瑞金医院妇产科, 上海 200025
  • 出版日期:2011-06-28 发布日期:2011-06-27
  • 通讯作者: 刘 延, 电子信箱: liuyan_dr@yahoo.com.cn。
  • 作者简介:吴诗瑜（1971—）, 女, 主治医师, 硕士；电子信箱: wushiyu317@hotmail.com。

Meta-analysis of correlation between tea consumption and risk of ovarian cancer

WU Shi-yu1, LI Miao-zhu2, LIU Yan3, WEI Ming-xiu1   

  1. 1.Department of Gynecology, Ruijin Hospital Luwan Branch, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China；2.Institute for Nutritional Sciences, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China；3.Department of Obstetrics and Gynecology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2011-06-28 Published:2011-06-27

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摘要：

目的 通过Meta分析研究饮茶与卵巢癌患病风险的相关性。方法 在Pubmed、EMbase、CBMdisc、CNKI、万方数据库检索相关文献，建立一定的筛选标准，在群体研究中探究卵巢癌发病风险与饮茶的关系。检索年限为1995—2010年，采用RevMan 5.1.0软件完成Meta分析。结果 共纳入国内外病例对照试验和队列试验9项研究，包括69 786例参与者，其中病例4 571例，对照65 215例。Meta分析显示：饮用茶可以显著地降低女性患卵巢癌的风险（RR=0.82，95%CI=0.70~0.96，P<0.001）；其中绿茶降低患病风险的作用更为显著（RR=0.69，95%CI=0.54~0.90，P=0.006）。结论 饮用茶可以在一定程度上降低女性卵巢癌的患病风险，其中绿茶的抗癌效果更为显著。

关键词: 卵巢癌, 茶, 抗癌, Meta分析

Abstract:

Objective To explore the correlation between tea consumption and risk of ovarian cancer through Meta-analysis. Methods Relative studies published between 1995 and 2010 about tea consumption and risk of ovarian cancer were searched in Pubmed, EMbase, CBMdisc, CNKI and Wanfang Data. All reports were systemically reviewed, and Meta-analysis was performed by RevMan 5.1.0 software. Results A total of 9 domestic and overseas case-control studies and cohort studies were included, with 4 571 cases and 65 215 controls. Meta-analysis revealed that tea consumption significantly decreased the risk of ovarian cancer (RR, 0.82; 95%CI, 0.70-0.96; P<0.001), and the effect was more significant for green tea consumption (RR, 0.69; 95%CI, 0.54-0.90; P=0.006). Conclusion Tea consumption, especially green tea consumption, may reduce the risk of ovarian cancer.

Key words: ovarian cancer, tea, anti-cancer, Meta-analysis