›› 2019, Vol. 39 ›› Issue (10): 1214-.doi: 10.3969/j.issn.1674-8115.2019.10.020

• Review • Previous Articles     Next Articles

Advances in research on relationship between osteoporosis and intestinal microbe

LI Zi-lin1, GU Wen-qing2, SHEN Tian1   

  1. 1. Shanghai Jiao Tong University School of Public Health, Shanghai 200025, China; 2. Fenglin Street Community Health Service Center, Xuhui District, Shanghai, Shanghai 200032, China
  • Online:2019-10-28 Published:2019-11-22
  • Supported by:
    National Natural Science Foundation of China, 71603167

Abstract: Osteoporosis, one of the severest diseases in the middle-aged and elderly population, is the result of the disorder of the normal bone turnover process. At present, many studies have shown that bone turnover is closely related to the microbial environment in the human body. The largest microbiota in the human body exists in the intestine and plays an important role in the normal physiological activities of the body, such as nutrition, metabolism, immunity and barrier. Intestinal microbe can regulate endocrine and immune system through a series of processes, thereby affecting the process of bone turnover in the body. This article briefly reviews the current research about the effects of intestinal microbe on the process of bone turnover in the body. It is expected to provide new ideas for the treatment of osteoporosisexploring the relationship between osteoporosis and intestinal microbe.

Key words: osteoporosis, bone turnover, intestinal microbe

CLC Number: