上海交通大学学报（医学版）

上海交通大学学报（医学版）

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从SYMPLICITY HTN-3谈经导管去肾交感神经术的现状与未来

黄晶,李京波   

  1. 上海交通大学 附属第六人民医院心内科， 上海 200233
  • 出版日期:2016-04-28 发布日期:2016-05-26
  • 通讯作者: 李京波, 电子信箱: lijb@sjtu.edu.cn。
  • 作者简介:黄晶（1991—）， 男， 博士生; 电子信箱: jiladahe0528@126.com。

Current status and future of catheter-based renal denervation from the perspective of SYMPLICITY HTN-3

HUANG Jing, LI Jing-bo   

  1. Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
  • Online:2016-04-28 Published:2016-05-26

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摘要：

高血压是常见的心血管疾病之一，也是冠状动脉粥样硬化性心脏病、脑卒中等多种疾病的重要危险因素，而顽固性高血压又是高血压治疗和管理中较为棘手的一个问题。近年来，经导管去肾交感神经术（RDN）的出现开启了治疗顽固性高血压的新篇章，但SYMPLICITY HTN-3研究的阴性结果却掀起了众多专家学者对RDN的质疑和激烈的争论。该文透过SYMPLICITY HTN-3探讨经导管RDN术目前的研究现状及未来的发展方向。

关键词: 经导管去肾交感神经术, 顽固性高血压, SYMPLICITY HTN-3

Abstract:

Hypertension is one of the most common cardiovascular diseases and a key risk factor of many diseases such as coronary atherosclerotic heart disease and stroke. However, resistant hypertension is an intractable problem in the management and treatment of hypertension. In recent years, with the advent of catheter-based renal denervation (RDN), a new chapter has been opened for the treatment of resistant hypertension, but the negative result of SYMPLICTY HTN-3 study has led to doubts and drastic debates on RDN. This paper reviews current status and future directions of catheter-based RDN studies through SYMPLICTY HTN-3.

Key words: catheter-based renal denervation, resistant hypertension, SYMPLICTY HTN-3