上海交通大学学报(医学版) ›› 2022, Vol. 42 ›› Issue (5): 680-684.doi: 10.3969/j.issn.1674-8115.2022.05.018

• 综述 • 上一篇    下一篇

获得性囊性肾病相关肾细胞癌的研究进展

向晗1(), 向武2, 张伟国1()   

  1. 1.陆军军医大学大坪医院放射科,重庆 400042
    2.重庆市北碚区中医院康复科,重庆 400799
  • 收稿日期:2022-01-17 接受日期:2022-04-18 出版日期:2022-05-28 发布日期:2022-05-28
  • 通讯作者: 张伟国 E-mail:903274184@qq.com;wgzhang01@163.com
  • 作者简介:向 晗(1995—),女,硕士生;电子信箱:903274184@qq.com
  • 基金资助:
    重庆市影像医学与核医学临床研究中心项目(CSTC2015YFPT-gcjsyjzx0175)

Research progress in acquired cystic disease-associated renal cell carcinoma

XIANG Han1(), XIANG Wu2, ZHANG Weiguo1()   

  1. 1.Department of Radiology, Daping Hospital, Army Medical University, Chongqing 400042, China
    2.Department of Rehabilitation, Chongqing Beibei Traditional Chinese Medical Hospital, Chongqing 400799, China
  • Received:2022-01-17 Accepted:2022-04-18 Online:2022-05-28 Published:2022-05-28
  • Contact: ZHANG Weiguo E-mail:903274184@qq.com;wgzhang01@163.com
  • Supported by:
    Fund of Chongqing Clinical Research Centre of Imaging and Nuclear Medicine(CSTC2015YFPT-gcjsyjzx0175)

摘要:

获得性囊性肾病相关肾细胞癌(acquired cystic disease-associated renal cell carcinoma,ACD-RCC)是终末期肾病及获得性囊性肾病患者最常见的肾脏肿瘤类型,2016年作为一种新的肾癌亚型纳入世界卫生组织肾脏肿瘤分类中。虽然该病是一种低度恶性肿瘤,但也可能出现局部复发或远处转移。对于长期透析尤其是并发症少的年轻患者,应定期行影像学监测,早期发现病变,早期干预,改善患者预后,提高其生存质量。目前,国内外文献主要聚焦在其临床病理方面,对该病影像特征、预后及监测方面的研究有限。该文归纳总结了ACD-RCC的流行病学特征、病因、病理特征、影像表现、治疗方法、预后及监测方法,旨在帮助临床医师更全面地认识ACD-RCC,为ACD-RCC的诊疗及监测提供参考。

关键词: 获得性囊性肾病, 肾细胞癌, 影像特征, 预后

Abstract:

Acquired cystic disease-associated renal cell carcinoma (ACD-RCC) is the most common type of RCC seen in patients with end-stage renal disease and acquired cystic kidney disease, and was added to the list of RCC subtypes in the 2016 World Health Organization classification. ACD-RCC is generally believed to be indolent, however, some tumors may show local recurrence and distant metastasis. Periodic screening should be performed in dialysis patients, especially in younger patients with minor comorbidities, early detection and early intervention can improve the prognosis and quality of life. Literatures published at home and abroad mainly focused on it's clinicopathological features, there is scarce research describing the imaging appearance, prognosis and surveillance of ACD-RCC. This paper summarizes the epidemiology, etiology, pathological features, imaging manifestations, treatment, prognosis and surveillance of ACD-RCC, and aims to provide a compressive understanding of the disease for clinicians.

Key words: acquired cystic disease, renal cell carcinoma, image features, prognosis

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