综述

磁共振波谱技术对γ-氨基丁酸在精神疾病中的研究进展

  • 张宗凤 ,
  • 范青 ,
  • 王媛 ,
  • 张海音 ,
  • 王振 ,
  • 肖泽萍
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  • 上海交通大学 医学院附属精神卫生中心, 上海市精神疾病临床医学中心, 上海200030
张宗凤(1990—), 女, 硕士生; 电子信箱: zzf19900713@163.com

网络出版日期: 2015-12-22

基金资助

 国家自然科学基金 (81171280,81301153);国家临床重点专科-上海市精神卫生中心(卫生部医政司2011-873);上海市精神卫生中心重点特色专科(2013-YJTSZK-02)

Advances of γ-aminobutyric acid of patients with mental disorders by magnetic resonance spectroscopy technology

  • ZHANG Zong-feng ,
  • FAN Qing ,
  • WANG Yuan ,
  • ZHANG Hai-yin ,
  • WANG Zhen ,
  • XIAO Ze-ping
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  • Shanghai Mental Health Center, Shanghai Clinical Center for Mental Disorders, Shanghai Jiao Tong University School of Medicine, Shanghai200030, China

Online published: 2015-12-22

Supported by

National Natural Science Foundation of China, 81171280, 81301153; National Key Clinical Disciplines at Shanghai Mental Health Center, OMA-MH 2011-873; The Key Characteristic Specialist Department of Shanghai Mental Health Center, 2013-YJTSZK-02

摘要

脑内γ-氨基丁酸能神经元功能的异常见于多种精神疾病,如焦虑障碍、心境障碍、睡眠障碍、精神分裂症、孤独症谱系障碍及强迫症等。利用磁共振波谱技术研究γ-氨基丁酸在精神疾病中的作用取得了一定进展,该文对此进行综述。

本文引用格式

张宗凤 , 范青 , 王媛 , 张海音 , 王振 , 肖泽萍 . 磁共振波谱技术对γ-氨基丁酸在精神疾病中的研究进展[J]. 上海交通大学学报(医学版), 2015 , 35(10) : 1565 . DOI: 10.3969/j.issn.1674-8115.2015.10.027

Abstract

The abnormalities of functions of γ-aminobutyric acid neurons in the brain are found in a variety of mental disorders, such as anxiety disorder, mood disorder, sleep disorder, schizophrenia, autism spectrum disorder, and obsessive-compulsive disorder, etc. This paper reviews advances in studies on the effects of γ-aminobutyric acid on mental disorders by the magnetic resonance spectroscopy technology.

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