白假丝酵母菌唑类耐药相关的转录调控研究进展
网络出版日期: 2016-03-29
基金资助
上海市重点专科配套课题(ZK2012A21);上海市科委基金(15ZR1426900);上海黄浦区卫生局基金(2012-HGG-44);上海市黄浦区卫生系统优秀青年人才培养计划(RCPY1407)
Research advances in transcription regulation related to azole resistance of Candida albicans
Online published: 2016-03-29
Supported by
Project of Shanghai Key Specialty, ZK2012A21; Foundation of Shanghai Municipal Science and Technology Commission, 15ZR1426900; Foundation of Shanghai Municipal Huangpu District Health Bureau, 2012-HGG-44; Shanghai Municipal Huangpu District Health System Program for Youths, RCPY1407
刘锦燕 , 史册 , 王影 , 等 . 白假丝酵母菌唑类耐药相关的转录调控研究进展[J]. 上海交通大学学报(医学版), 2016 , 36(2) : 291 . DOI: 10.3969/j.issn.1674-8115.2016.02.027
In recent 30 years, Candida albicans has become the most common opportunistic pathogen that causes the incidence and mortality of patients with low immunity. With the frequent use of azole antifungal drugs, azole-resistant strains are often detected. Studies on the mechanism of drug resistance have drawn more and more attention. In recent years, studies on the mechanism of transcriptional regulation have also made great progress. The cis-acting elements and trans-acting factors of the resistant-related encoding gene were identified and the acting mechanism was partially elucidated. In this paper, research advances in the transcription regulation related to azole resistance of Candida albicans are reviewed.
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