目的 · 分析胃恶性肿瘤患者的临床特征以及病理学特征，为开展胃恶性肿瘤研究以及规范化防治工作提供参考。方法 · 收集 2005-2014 年间上海交通大学医学院附属瑞金医院住院病史登记系统内的胃恶性肿瘤资料，采集患者基本人口学信息、家族史、户 籍所在地以及临床病理诊断等信息，进行人口学资料分析和临床病理资料分析。结果 · 胃恶性肿瘤患者 3 315 例，年龄分布在 18~98 岁（平均年龄为59.71 岁）。男性2 184 例，女性1 131 例，每年新增病例男女构成比在1.63:1~2.45:1。病理诊断显示胃癌3 122 例 （94.2%），其余为胃肠间质瘤（5.5%）、胃肠神经内分泌肿瘤（0.2%）和胃肠恶性淋巴瘤（0.1%）。胃癌家族史占 4.46%。结论 · 从临 床特征以及病理学特征分析，胃癌占胃恶性肿瘤 94% 以上，与年龄、性别、家族史等因素相关。

 Objective · To analyze clinical and pathological characteristics of gastric malignancies from a single center of Ruijin Hospital, and provide references for making healthy policy on gastric tumors.  Methods · The data sources were from hospital in-patients database including demographic information, family history, clinicopathological information, and census registering information during 2005 to 2014. The demographic data and clinicopathological data were analyzed.  Results · The total number was 3 315 cases with gastric malignancies (2 184 male patients and 1 131 female patients). It was about 2 times as high in males as in females. The patient age was between 18 to 98 years old (mean 59.71 years old). Based on pathologic diagnosis, 3 122 cases (94.2%) were gastric adenocarcinoma, others were gastrointestinal stromal tumors (5.5%), neuroendocrine tumor (0.2%) and malignant lymphoma (0.1%). Out of patients with gastric carcinoma, about 4.46% of cases ran in families.  Conclusion · Over 94% cases of gastric malignancies are gastric carcinomas. Specific risk profiles of gastric carcinomas include age, gender and family factors.