论著·临床研究

病程12个月及以上非小细胞肺癌患者生活质量评估及影响因素研究

  • 何亚平 1 ,
  • 楼玮群 2 ,
  • 陈杰灵 2 ,
  • 周箴 3 ,
  • 朱静芬 1 ,
  • 简红 3
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  • 1. 上海交通大学公共卫生学院,上海200025;2. 上海交通大学附属胸科医院上海市胸科医院肿瘤科,上海200030;3. 香港大学社会工作与社会行政学系,香港
何亚平(1964—),女,副教授,博士;电子信箱:hypcyr@sina.com。

网络出版日期: 2018-07-30

基金资助

上海市卫生和计划生育委员会科研项目(201740116);上海交通大学医学院教育研究重点项目(ZD150603)

Influencing factors for quality of life in patients over 12 months after diagnosis of non-small cell lung cancer

  • HE Ya-ping1 ,
  • LOU Wei-qun2 ,
  • CHEN Jie-ling2 ,
  • ZHOU Zhen3 ,
  • ZHU Jing-fen1 ,
  • JIAN Hong3
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  • 1. School of Public Health, Shanghai Jiao Tong University, Shanghai 200025, China; 2. Department of Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China; 3. Department of Social Work & Social Administration, The University of Hong Kong, Hong Kong, China

Online published: 2018-07-30

Supported by

Shanghai Municipal Health and Family Planning Commission Foundation, 201740116; Shanghai Jiao Tong University School of Medicine Core Education Project, ZD150603

摘要

目的·评估首诊至调查时间病程≥12个月的非小细胞肺癌(non-small cell lung cancer,NSCLC)患者的生活质量,探讨相关影响因素。方法·采用FACT-L(Functional Assessment of Cancer Therapy–Lung)量表对111名纳入研究的患者的生活质量进行评价,自制问卷收集患者人口学特征、医疗信息和情绪感受。结果·研究从治疗及患者主观感受2个路径探讨NSCLC患者生活质量的影响因素。单因素Logistic回归分析显示低生活质量的风险因素为:自卑孤独感、骨转移、病理类型、化学治疗周期、年龄、共住家庭成员结构和经济困难。结论·肺癌患者生活质量影响因素多元而广泛,情绪及症状管理亟待重视。

本文引用格式

何亚平 1 , 楼玮群 2 , 陈杰灵 2 , 周箴 3 , 朱静芬 1 , 简红 3 . 病程12个月及以上非小细胞肺癌患者生活质量评估及影响因素研究[J]. 上海交通大学学报(医学版), 2018 , 38(7) : 775 . DOI: 10.3969/j.issn.1674-8115.2018.07.010

Abstract

Objective · To examine quality of life and its influencing factors in patients over 12 months after diagnosis of non-small cell lung cancer (NSCLC). Methods · A total of 111 patients included in the study completed the self-reported measures. Quality of life was measured using Functional Assessment of Cancer Therapy–Lung. Other measures included socio-demographic characteristics, disease- and treatment-related information, and emotional feelings. Results · The factors influencing the quality of life of NSCLC patients were investigated two approaches: treatment and subjective feeling. Univariate Logistic regression analysis found the risk factors for low quality of life included sense of low self-esteem and loneliness, bone metastasis, pathological type, chemotherapy cycle, age, cohabitant type and financial burden. Conclusion · The factors associated with quality of life in lung cancer patients are diverse and extensive, and it warrants attention on psychological support and symptom management for these patients.
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