Research progress of regulation of osteoblast differentiation and proliferation
Online published: 2011-10-27
王勇平, 欧阳元明, 蒋 垚 . 成骨细胞分化及增殖调控的研究进展[J]. 上海交通大学学报(医学版), 2011 , 31(10) : 1465 . DOI: 10.3969/j.issn.1674-8115.2011.10.024
During bone metabolism and bone remodeling, mesenchymal cells differentiate into osteoblasts under certain conditions, which play an important role in bone formation. The normal bone remodeling and part of the bone pathological changes are closely related to osteoblast differentiation and proliferation. Osteoblast differentiation and proliferation are regulated by a variety of systemic and regional factors. Recent progress of regulation of osteoblast differentiation and proliferation is reviewed in this paper.
Key words: osteoblast; differentiation; proliferation; regulation
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