硒结合蛋白1作为肿瘤标志物的研究进展
网络出版日期: 2013-02-06
Research progress on selenium binding protein 1 as a novel tumor biomarker
Online published: 2013-02-06
张晨静, 潘 驰, 潘文胜, 等 . 硒结合蛋白1作为肿瘤标志物的研究进展[J]. 上海交通大学学报(医学版), 2013 , 33(1) : 114 . DOI: 10.3969/j.issn.1674-8115.2013.01.023
Selenium binding protein 1 (SBP1) has been shown to bind selenium covalently and is expressed in a variety of tissues and cell lines. Selenium is incorporated into selenoproteins that have a wide range of pleiotropic effects, including its important function in prevention of cancer progression. Recent studies have revealed that SBP1 may not only exert tumor suppressive function, but also become a novel biomarker for predicting prognosis and guiding personalized therapeutic strategies. This paper briefly reviews the studies of SBP1 as a novel biomarker and tumor suppressor in the progression of various cancers.
Key words: selenium binding protein 1; personalized biomarker; anti-tumor; prediction
/
〈 |
|
〉 |