›› 2012, Vol. 32 ›› Issue (2): 155-.doi: 10.3969/j.issn.1674-8115.2012.02.007

• Original article (Clinical research) • Previous Articles     Next Articles

Prevalence of age-related macular degeneration in Beixinjing Community of Shanghai

HUANG Xiao-bo1, ZOU Hai-dong1, WANG Ning1, WANG Wei-wei2, FU Jiong2, SHEN Bing-jie2, XU Xun1, ZHANG Xi1   

  1. 1.Department of Ophthalmology, the First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China；2.Beixinjing Community Health Service Center of Changning District, Shanghai 200335, China
  • Online:2012-02-28 Published:2012-02-28
  • Supported by:

    Foundation from the Ministry of Health, 200801；Shanghai Clinical Medicine Center for Vision Rehabilitation, FM-040102-305；Shanghai Key Laboratory for Ocular Fundus Diseases Foundation, 07Z22911

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Abstract:

Objective To investigate the prevalence of age-related macular degeneration (AMD) in residents aged ≥60 years in Beixinjing Community of Shanghai. Methods The prevalence and related factors of AMD in residents aged ≥60 years in Beixinjing Community of Shanghai were investigated between November 2007 and April 2008 with cluster sampling. An interview concerning general data, history of diagnosis and treatment of eye diseases, daily living visual acuity and corrected visual acuity was carried out. Basic eye examination was performed, and 2 photographs covering 45° of posterior eye fundus area were acquired in each eye with fundus camera. The diagnosis of AMD was made by two or more ophthalmologists, and the classification of AMD was based on the criteria from Chinese Eye Fundus Diseases Group. Results A total of 4 153 residents were included, and 3 571 finished examinations, with the examination rate of 85.99%. Four hundred and seventy-seven patients (778 eyes) were diagnosed as AMD, accounting for 13.36% of the residents finishing examinations. Sixty-four patients (85 eyes) were diagnosed as exudative AMD, occupying 1.79% of the residents finishing examinations. The prevalences of AMD in the age groups of 60-69, 70-79 and no less than 80 were 6.23%, 14.98%, and 29.91%, respectively, with significant differences (χ2=169.40, P<0.01). The prevalences of AMD in the education groups of illiterate, primary school, middle school, and higher than middle school were 15.2%, 18.75%, 9.36% and 8.22%, respectively, with significant differences (χ2=59.56, P<0.01). There was no significant difference in the prevalences of AMD between males and females (χ2=0.03, P>0.05). In eyes of AMD, 3.08% and 18.51% were identified as blind or low vision. In eyes of exudative AMD, 15.29% and 32.95% were identified as blind or low vision, which were higher than those in eyes of atrophic AMD (1.59% and 16.73%). Conclusion The prevalence of AMD increases with age, and decreases with education level. AMD may lead to severe visual acuity impairment.

Key words: macular degeneration, aged, prevalence, visual acuity, data collection