• Review • Previous Articles     Next Articles

Application of hepatic stem cells and spermatogonial stem cells in treatment of liver disease

ZHANG Zhen-zhen, CHEN Zheng, YUAN Qing-qing, SUN Min, NIU Ming-hui, HE Zu-ping   

  1. State Key Laboratory of Oncogenes and Related Genes, Med-X-Renji Hospital Clinical Stem Cell Research Center, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
  • Online:2016-09-28 Published:2016-10-31
  • Supported by:

    National Nature Science Foundation of China,31171422; Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support,20152511


Severe shortage of liver donors and hepatocytes has become a major handicap for the treatment of liver disease. Extra-liver tissues and stem cells can provide an essential source of hepatocytes, which brings new promise for treating liver-related disease. Here we address the advances on the potential application of hepatic stem cells, spermatogonial stem cells, and other stem cells in the treatment of liver disease and future research directions based on studies from home and abroad, as well as our research.

Key words: hepatic stem cells, spermatogonial stem cells, liver disease, cell therapy