Abstract:

Objective To investigate clinical antibiotic use and assess management efficacy in obstetrical and gynecological hospitals before and after the special antibiotic rectification. Methods The data of clinical antibiotic use in the hospital information system from 2010 to 2014 were retrieved and retrospectively analyzed and summarized according to indexes proposed by the 2011 National Special Rectification Program for Clinical Antibiotic Use. Results The ratios of the amount of used antibiotics to the total amount and clinical antibiotic prescriptions to total prescriptions and antibiotic use rates in inpatients and type Ⅰ incision operations decreased from 18.53%, 16.54%, 73.53% and 67.17% before rectification (2010) to 3.75%, 8.82%, 41.25% and 11.88% after rectification (2014), respectively, which met the requirements of the National Health and Family Planning Commission. The decline tendency was statistically meaningful (P=0.000). Other indexes such as antibiotic use density (AUD) and sample test rates for patients received antibiotic therapy were also achieved the requirements of the National Health and Family Planning Commission. Conclusion The clinical antibiotic use is more reasonable and the management efficacy is significant via the special antibiotic rectification.

Key words: special rectification on antibiotics use, management measure, rational drug use, efficacy analysis