Objective  To understand the supportive care needs and quality of life of first-visit patients diagnosed with gynecologic cancer and explore the correlation between supportive care needs and quality of life. Methods  The convenience sampling method was adopted to select 123 first-visit patients who were diagnosed with gynecologic cancer from June 2014 to February 2015 in 3 grade A tertiary general hospitals. Patients were surveyed by questionnaires of supportive care needs survey (SCNS) and functional assessment of cancer therapy (FACT-G, V4.0).  Results  The average score of supportive care needs of first-visit patients diagnosed with gynecologic cancer was 2.63±0.65 and the unsatisfactory rate of health information needs was the highest. The total score of quality of life was 71.53±10.74. Dimensions of supportive care needs (except social/family circumstances) negatively correlated with those of quality of life (P<0.01) and physical and daily living needs and psychological needs significantly affected the quality of life. Conclusion  The degree of supportive care needs of first-visit patients diagnosed with gynecologic cancer is different. Physical and daily living needs and psychological needs are key influencing factors of the quality of life. Medical staff should provide personalized assistance and psychological guidance to improve the quality of life.