Review

ACE2/Apelin signaling and atherosclerosis

  • ZHANG Zhen-zhou ,
  • SONG Bei ,
  • ZHONG Jiu-chang
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  • State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Hypertension, Shanghai 200025, China

Online published: 2016-07-25

Supported by

National Major Research Plan Training Program, 91339108;  National Basic Research Program of China, 2014CB542300; National Natural Science Foundation of China, 81370362, 81170246; Scientific Research Project of Health Bureau of Shanghai, 201440368

Abstract

Atherosclerotic diseases have become the leading cause of human death. The renin-angiotensin system is an important factor for promoting the occurrence and development of atherosclerotic cardiovascular diseases. Studies have revealed that the ACE2/Apelin signaling plays a protective role in the cardiovascular system. This article reviews the latest research advances in ACE2/Apelin signaling and its regulatory role in atherosclerosis.

Cite this article

ZHANG Zhen-zhou , SONG Bei , ZHONG Jiu-chang . ACE2/Apelin signaling and atherosclerosis[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2016 , 36(6) : 917 . DOI: 10.3969/j.issn.1674-8115.2016.06.026

Outlines

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