Original article (Clinical research)

Robotic-assisted versus laparoscopic radical prostatectomy: a meta-analysis

  • CHU Jing-jing ,
  • YE Chao ,
  • JIN Wen ,
  • YIN Xi
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  • Department of Medical Record, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China

Online published: 2017-01-19

Supported by

Major Science and Technology Projects of Zhejiang Province, 2013C33122

Abstract

Objective · To assess the outcomes of robotic-assisted laparoscopic prostatectomy (RALP)and laparoscopic radical prostatectomy (LRP). Methods · Databases including PubMed, Web of Science, Cochrane Library, EMbase, EBSCO, CINAHL, CNKI , WangFang and VIP Database were searched to collect the controlled studies on RALP for localized prostate cancer. Meta-analysis was applied using the Review Manager V5.3 software in accordance with the Cochrane Collaboration. Results · A total of 15 studies were identified, including 1 621 cases of RALP and 1 894 cases of LRP. The results of meta-analysis showed that, compared to LRP, operative blood loss[WMD=-120.29, 95% CI (-182.20, -58.39), P=0.0001] and transfusion rate[OR=0.44, 95% CI (0.25, 0.79), P=0.006] were lower in RALP. Moreover, RALP was associated with significantly improved outcomes in the postoperative urinary continence rate of 3-month, 6-month, 12- month[OR=2.76, 95% CI (1.99, 3.82), P<0.000 01; OR=2.50, 95% CI (1.72, 3.63), P<0.000 01; OR=2.28, 95% CI (1.51, 3.46), P<0.000 1]. But there were no significant differences between the two techniques in operation time, rate of positive surgical margins and complication (P>0.05). Conclusion · RALP showed benefits in terms of operative blood loss, transfusion rate as well as functional outcomes. Further studies of larger populations with a longer follow-up are needed to make any statement.

Cite this article

CHU Jing-jing , YE Chao , JIN Wen , YIN Xi . Robotic-assisted versus laparoscopic radical prostatectomy: a meta-analysis[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2017 , 37(1) : 64 . DOI: 10.3969/j.issn.1674-8115.2017.01.014

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