Journal of Shanghai Jiao Tong University (Medical Science) >

2018 , Vol. 38 >Issue 6: 685

DOI: https://doi.org/10.3969/j.issn.1674-8115.2018.06.018

Review

Roles of neurosteroids in the treatment of depressive episodes

  • CUI Lü-chun1 ,
  • HONG Wu1 ,
  • FANG Yi-ru1 ,
  • 2 ,
  • 3
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  • 1. Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China; 2. State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; 3. Shanghai Key Laboratory of Psychotic Disorders, Shanghai 200030, China

Online published: 2018-07-03

Supported by

Foundation of Ministry of Science and Technology of China, 2016YFC1307100; National Natural Science Foundation of China, 81771465

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Abstract

Neurosteroids are the key molecules in the central nervous system that modulate neural functions. They can influence human mood and behavior in various physiological and pathophysiological situations. Neurosteroids have been implicated in the pathogenesis of depressive episodes, providing innovative therapies for psychiatric disorders such as depressive disorder and bipolar disorder. This paper reviewed the research progress on therole of neurosteroids in the treatment of depressive episodes.

Key words： depressive episode; neurosteroid; depressive disorder; bipolar disorder

Cite this article

CUI Lü-chun1 , HONG Wu1 , FANG Yi-ru1 , 2 , 3 . Roles of neurosteroids in the treatment of depressive episodes[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2018 , 38(6) : 685 . DOI: 10.3969/j.issn.1674-8115.2018.06.018

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