Journal of Shanghai Jiao Tong University (Medical Science) >

2019 , Vol. 39 >Issue 8: 914

DOI: https://doi.org/10.3969/j.issn.1674-8115.2019.08.018

Review

Genetic research progress of depression

  • YU Ling-fang ,
  • ZHANG Chen
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  • Biochemical Pharmacology Laboratory, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China

Online published: 2019-09-23

Supported by

National Natural Science Foundation of China, 81471358；Western Medicine Guide Project of Shanghai Municipal Commission of Science and Technology; Shanghai Municipal Education Commission— Gaofeng Clinical Medicine Support, 20152530; Foundation of Shanghai Municipal Commission of Health and Family Planning, 201540029

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Abstract

Depression is a common mental disorder and causes great disease burden. To date peoples understanding of genetic mechanisms of depression is lagging far behind that of other psychiatric disorders such as schizophrenia and bipolar disorder. Recently, with the accumulation of clinical samples and the advances of methodology and technology, certain progress in genetics of depression has been made. This review summarizes the genetic research progress in candidate genes, common variants, rare variants and chromosome structure variations of depression.

Key words： depression; genetics; research progress

Cite this article

YU Ling-fang , ZHANG Chen . Genetic research progress of depression[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2019 , 39(8) : 914 . DOI: 10.3969/j.issn.1674-8115.2019.08.018

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