Journal of Shanghai Jiao Tong University (Medical Science) >

2021 , Vol. 41 >Issue 4: 497 - 501

DOI: https://doi.org/10.3969/j.issn.1674-8115.2021.04.013

Clinical research

Correlation between sleep quality and everyday cognitive function in perimenopausal and postmenopausal women

  • Wen-jun HUANG ,
  • Su-su JIANG ,
  • Min-fang TAO
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  • Department of Gynecology and Obstetrics, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200030, China

Received date: 2020-07-30

  Online published: 2021-05-14

Supported by

Project of Shanghai Municipal Health Commission(20184Y0362)

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Abstract

Objective

· To evaluate the correlation between sleep quality and everyday cognitive function in perimenopausal and postmenopausal women.

Methods

· Two hundred and eighty one women who visited the menopause clinic of Shanghai Sixth People's Hospital for the first time were included in the study. Socialdemographic characteristics of the patients were obtained by using the general information questionnaire. Pittsburgh Sleep Quality Index (PSQI) was used toassess sleep quality and its seven dimensions (sleep latency, sleep duration, sleep efficiency, sleep disturbance, subjective sleep quality, sleep medicationand daytime dysfunction).Everyday cognitive function was assessed by using the short version of Everyday Cognition (Ecog-12). Mann-Whitney U (two independent samples) or Kruskal-Wallis H (multiple indepentdent samples) test was used for univariate analysis of patents' everyday cogitive function.Spearman rank correlation was used to analyze the relationship of sleep quality and its seven dimensions with everyday cognitive function.Multiple linear stepwise regressionwas used to analyze the influencing factors of everyday cognitive function.

Results

· The Ecog-12 score of 281 women was 1.42 (1.17,1.67). The score of PSQI was 6.0 (3.0, 10.0). 40.9% of perimenopausal and postmenopausal women had poor sleep quality (PSQI≥8). There was no statisticaldifference in patients' everyday cognitive function among all social demographic characteristic variables (age, body mass index, monthly income, occupationstatus, educational level, menopausal status, parity, regular exercise and history of chronic diseases). Compared to women with good sleep quality,women with poor quality scored higher in Ecog-12 (P=0.000). Spearman correlation analysis showed that the scores of 7 dimensions of PSQI and totalscore of PSQI were positively correlated with Ecog-12 score (P=0.000). Multiple linear regression analysis showed that the explanation rate of sleep medication and daytime dysfunction on everyday cognitive function deline was 12.6%.

Conclusion

· Sleep medication and daytime dysfunction are the independent influencing factors of everyday cognitive function decline in perimenopausal and postmenopausal women. Perimenopausal and postmenopausal women with sleep disturbance should take sleep medication considerately, actively improve sleep quality, maintain good daytime function, andavoid or reduce cognitive impairment caused by sleep problems.

Key words： perimenopause; postmenopause; sleep quality; everyday cognitive function; sleep medication; daytime dysfunction

Cite this article

Wen-jun HUANG , Su-su JIANG , Min-fang TAO . Correlation between sleep quality and everyday cognitive function in perimenopausal and postmenopausal women[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2021 , 41(4) : 497 -501 . DOI: 10.3969/j.issn.1674-8115.2021.04.013

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