Journal of Shanghai Jiao Tong University (Medical Science) >

2010 , Vol. 30 >Issue 11: 1428

DOI: https://doi.org/10.3969/j.issn.1674-8115.2010.11.027

Review

Research progress of role of matrix metalloproteinase 7 in tumors

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  • Cancer Institute, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China

Online published: 2010-11-29

Supported by

National Natural Science Foundation of China, 30973382

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Abstract

Matrix metalloproteinase 7 (MMP7) plays an important role in tumorigenesis, tumor development and resistance to some anti-tumor medicine by degrading proteins of extracellular matrix and blocking fas/fasl apoptosis signal pathway. This paper discusses the mechanisms by which MMP7 contribute to carcinogenesis, and the research progress of MMP7 in tumor treatment.

Key words： matrix metalloproteinase 7; fas/fasl; apoptosis; neoplasm

Cite this article

HUANG Yong, ZHENG Shu . Research progress of role of matrix metalloproteinase 7 in tumors[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2010 , 30(11) : 1428 . DOI: 10.3969/j.issn.1674-8115.2010.11.027

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