Pathogenesis of complications of pre-eclampsia and eclampsia
Online published: 2011-05-27
Pre-eclampsia is a disorder that is unique to pregnancy, with gestational hypertension and proteinuria as main clinical manifestations. Without proper management, pre-eclampsia may develop to eclampsia and cause a series of complications involving cardiovascular, renal, neurologic, hematologic and gastrointestinal systems, which may threaten lives of mothers and infants. The pathogenesis of pre-eclampsia is still unclear, and reduced placental perfusion is considered to be the pathological mechanism, which may result in endothelial cell injury and further aggravate dysfunction of maternal systems. This paper reviews the pathogenesis, incidence and research progress of complications of pre-eclampsia and eclampsia.
Key words: pre-eclampsia; eclampsia; complication
LE Yi-ping, LIN Jian-hua . Pathogenesis of complications of pre-eclampsia and eclampsia[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2011 , 31(5) : 676 . DOI: 10.3969/j.issn.1674-8115.2011.05.032
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