%A GUO Qiu-man, SHU Rong %T Study on expressions of IL-17 in gingival tissue of patients with different types of periodontitis %0 Journal Article %D 2014 %J Journal of Shanghai Jiao Tong University (Medical Science) %R 10.3969/j.issn.1674-8115.2014.10.022 %P 1525- %V 34 %N 10 %U {https://xuebao.shsmu.edu.cn/CN/abstract/article_10499.shtml} %8 2014-10-28 %X

Objective To detect the distribution and expression of IL-17 in the gingival tissue of patients with different types of periodontitis and to preliminary explore the possible effects of IL-17 on the occurrence and development of periodontitis. Methods Gingival biopsies were divided into the control group (n=10), chronic periodontitis group (n=10), and aggressive periodontitis group(n=10). The distribution and expression of IL-17 in the gingival tissue of each group were detected by the immunohistochemistry. Results IL-17 expressed in the gingival epithelium and connective tissue full layer. The expressions of IL-17 in the gingival tissue of the chronic periodontitis group and aggressive periodontitis group were significantly higher than that of the control group (P<0.01). The expressions of IL-17 in the gingival epithelium and connective tissue of the aggressive periodontitis group were significantly higher than those of the chronic periodontitis group (P<0.01). Conclusion IL-17 involves in the occurrence and development of periodontal inflammation. The expressions of IL-17 in the gingival tissue of patients with different types of periodontitis are different.