%A ZHANG Wen-tian, LIAN Feng, XUE Song %T Research progresses of effects of placental growth factor on myocardial regeneration treatment after acute myocardial infarction %0 Journal Article %D 2014 %J Journal of Shanghai Jiao Tong University (Medical Science) %R 10.3969/j.issn.1674-8115.2014.10.026 %P 1543- %V 34 %N 10 %U {https://xuebao.shsmu.edu.cn/CN/abstract/article_10503.shtml} %8 2014-10-28 %X

Hypoxic condition of myocardial cells will stimulate myocardial cells and interstitial cells to release growth factors to induce angiogenesis and cardiac remodeling after acute myocardial infarction (AMI). Placental growth factor (PlGF) is a stress product after the injury of myocardial tissue. It can not only promote angiogenesis and regulate the inflammatory response, but also closely related to ventricular remodeling and paracrine mechanism of stem cells. This paper reviews the effects of PlGF on the myocardial regeneration treatment after AMI.