%A ZHANG Zhen-zhou, SONG Bei, ZHONG Jiu-chang %T ACE2/Apelin signaling and atherosclerosis %0 Journal Article %D 2016 %J Journal of Shanghai Jiao Tong University (Medical Science) %R 10.3969/j.issn.1674-8115.2016.06.026 %P 917- %V 36 %N 6 %U {https://xuebao.shsmu.edu.cn/CN/abstract/article_11199.shtml} %8 2016-06-28 %X

Atherosclerotic diseases have become the leading cause of human death. The renin-angiotensin system is an important factor for promoting the occurrence and development of atherosclerotic cardiovascular diseases. Studies have revealed that the ACE2/Apelin signaling plays a protective role in the cardiovascular system. This article reviews the latest research advances in ACE2/Apelin signaling and its regulatory role in atherosclerosis.