甲基转移酶3调控pri-miR-21甲基化修饰在糖尿病肾病肾脏纤维化中的作用

吴佳晋, 钟晨, 李大伟, 陈若洋, 瞿俊文, 张明

Role of methyltransferase like 3 regulating pri-miR-21 methylation in renal fibrosis of diabetes nephropathy

WU Jiajin, ZHONG Chen, LI Dawei, CHEN Ruoyang, QU Junwen, ZHANG Ming

图1 各组小鼠血糖、Scr、ACR及肾脏病理变化 Note： A. Analysis of blood glucose levels in the 4 groups. B. Analysis of Scr levels in the 4 groups. C. Analysis of ACR levels in the 4 groups. D. H-E staining, Masson staining and sirius red staining of kidneys in the 4 groups (×200). ①P=0.006, ②P=0.033, ③P=0.000, ④P=0.016, ⑤P=0.023.

Fig 1 Changes of blood glucose, Scr, ACR and kidney pathology in the mice of the 4 groups