微RNA-30b-5p通过靶向Atg5抑制多囊卵巢综合征大鼠卵巢颗粒细胞自噬

王雪敏, 王亚楠, 牛爱琴, 叶英, 李飞

MicroRNA-30b-5p inhibits autophagy in ovarian granulosa cells in polycystic ovary syndrome rats by targeting Atg5

WANG Xuemin, WANG Yanan, NIU Aiqin, YE Ying, LI Fei

图5 各组大鼠卵巢GC凋亡水平 Note：A. Detection of apoptosis by flow cytometry. B. GC apoptosis rate in each group. a—blank group; b—control group; c—miR-NC group; d—miR-30b-5p overexpression group; e—miR-30b-5p overexpression+pcDNA3.1-NC group; f—miR-30b-5p overexpression+pcDNA3.1-Atg5 group. ①P=0.000, compared with the blank group; ②P=0.000, compared with the control group; ③P=0.000, compared with the miR-30b-5p overexpression group.

Fig 5 Apoptosis levels of ovarian GC in rats in each group