短期GnRH脉冲治疗对先天性低促性腺激素性性腺功能减退症青少年期男性患者垂体⁃睾丸功能的作用

王斐, 龚艳, 许丽雅, 刘庆旭, 李妍, 郭盛, 李嫔

Effect of short-term GnRH pulse therapy on pituitary-testicular function in adolescent male patients with congenital hypogonadotropic hypogonadism

WANG Fei, GONG Yan, XU Liya, LIU Qingxu, LI Yan, GUO Sheng, LI Pin

图2 CHH患者持续GnRH脉冲治疗3个月期间LH、FSH和睾酮水平的变化 (n=5) Note： A. LH base value. B. LH peak value. C. FSH base value. D. FSH peak value. E. Testosterone level. ①P=0.023, ②P=0.005, ③P=0.014, ④P=0.012, ⑤P=0.006, ⑥P=0.022, ⑦P=0.004, ⑧P=0.045, compared with the level before GnRH pulse therapy.

Fig 2 Changes of LH, FSH and testosterone levels in the adolescent boys with CHH during the continuous GnRH pulse therapy for 3 months (n=5)