生命早期环境因素暴露与儿童哮喘关系的病例对照研究
邓云天, 熊文魁, 朱芮, 刘恩梅, 李雪梅, 钟朝晖

A case-control study of the relationship between early-life environmental exposure and childhood asthma
DENG Yuntian, XIONG Wenkui, ZHU Rui, LIU Enmei, LI Xuemei, ZHONG Zhaohui
表 2 重庆地区哮喘儿童生命早期室内环境暴露的单因素Logistic回归分析
Tab 2 Univariate Logistic regression of early-life in-door environment exposure for childhood asthma in Chongqing
Exposure itemAsthma (n=220)Control (n=636)OR (95%CIP value
Family second-hand smoke exposure/n (%)122 (55.5)251 (39.5)1.910 (1.401‒2.603)0.000
Second-hand smoke exposure level/n (%)
0 cig per day98 (44.5)385 (60.5)Reference
≥1 cig per day and <5 cig per day52 (23.6)120 (18.9)1.702 (1.148‒2.524)0.008
≥5 cig per day and <10 cig per day30 (13.6)61 (9.6)1.932 (1.184‒3.154)0.008
≥10 cig per day and <20 cig per day31 (14.1)62 (9.7)1.964 (1.210‒3.190)0.006
≥20 cig per day9 (4.1)8 (1.3)4.420 (1.662‒11.751)0.003
Bedroom air conditioner use/n (%)211 (95.9)575 (90.4)2.487 (1.214‒5.097)0.013
Dampness and mold points in bedroom/n (%)37 (16.8)47 (7.0)2.689 (1.695‒4.264)0.000
Seen cockroaches in bedroom/n (%)84 (38.2)145 (21.6)2.245 (1.617‒3.117)0.000
Room cleaning frequency/n (%)
6‒7 times per week95 (43.2)359 (53.4)Reference
3‒5 times per week114 (51.8)294 (43.8)1.469 (1.071‒2.015)0.017
<3 times per week11 (5.0)19 (2.8)2.271 (1.064‒4.846)0.034
Air purifier using frequency/n (%)
Never164 (74.5)435 (64.7)Reference
Only haze days44 (20.0)171 (25.5)0.691 (0.473‒1.010)0.056
Every day12 (5.5)66 (9.8)0.471 (0.248‒0.896)0.022
Home interior decoration/n (%)32 (14.5)64 (9.5)1.617 (1.026‒2.548)0.038