生命早期环境因素暴露与儿童哮喘关系的病例对照研究
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邓云天, 熊文魁, 朱芮, 刘恩梅, 李雪梅, 钟朝晖
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A case-control study of the relationship between early-life environmental exposure and childhood asthma
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DENG Yuntian, XIONG Wenkui, ZHU Rui, LIU Enmei, LI Xuemei, ZHONG Zhaohui
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表 2 重庆地区哮喘儿童生命早期室内环境暴露的单因素Logistic回归分析
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Tab 2 Univariate Logistic regression of early-life in-door environment exposure for childhood asthma in Chongqing
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Exposure item | Asthma (n=220) | Control (n=636) | OR (95%CI) | P value |
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Family second-hand smoke exposure/n (%) | 122 (55.5) | 251 (39.5) | 1.910 (1.401‒2.603) | 0.000 | Second-hand smoke exposure level/n (%) | | | | | 0 cig per day | 98 (44.5) | 385 (60.5) | Reference | ‒ | ≥1 cig per day and <5 cig per day | 52 (23.6) | 120 (18.9) | 1.702 (1.148‒2.524) | 0.008 | ≥5 cig per day and <10 cig per day | 30 (13.6) | 61 (9.6) | 1.932 (1.184‒3.154) | 0.008 | ≥10 cig per day and <20 cig per day | 31 (14.1) | 62 (9.7) | 1.964 (1.210‒3.190) | 0.006 | ≥20 cig per day | 9 (4.1) | 8 (1.3) | 4.420 (1.662‒11.751) | 0.003 | Bedroom air conditioner use/n (%) | 211 (95.9) | 575 (90.4) | 2.487 (1.214‒5.097) | 0.013 | Dampness and mold points in bedroom/n (%) | 37 (16.8) | 47 (7.0) | 2.689 (1.695‒4.264) | 0.000 | Seen cockroaches in bedroom/n (%) | 84 (38.2) | 145 (21.6) | 2.245 (1.617‒3.117) | 0.000 | Room cleaning frequency/n (%) | | | | | 6‒7 times per week | 95 (43.2) | 359 (53.4) | Reference | ‒ | 3‒5 times per week | 114 (51.8) | 294 (43.8) | 1.469 (1.071‒2.015) | 0.017 | <3 times per week | 11 (5.0) | 19 (2.8) | 2.271 (1.064‒4.846) | 0.034 | Air purifier using frequency/n (%) | | | | | Never | 164 (74.5) | 435 (64.7) | Reference | ‒ | Only haze days | 44 (20.0) | 171 (25.5) | 0.691 (0.473‒1.010) | 0.056 | Every day | 12 (5.5) | 66 (9.8) | 0.471 (0.248‒0.896) | 0.022 | Home interior decoration/n (%) | 32 (14.5) | 64 (9.5) | 1.617 (1.026‒2.548) | 0.038 |
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