丙型病毒性肝炎肝硬化失代偿期患者发生细菌感染的列线图预测模型构建及评价
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薛淋淋, 李秉翰, 常丽仙, 李卫昆, 刘春云, 刘立
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Construction and evaluation of a nomogram prediction model for bacterial infection in patients with decompensated hepatitis C cirrhosis
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XUE Linlin, LI Binghan, CHANG Lixian, LI Weikun, LIU Chunyun, LIU Li
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表2 丙肝肝硬化失代偿期患者发生细菌感染的单因素及多因素Logistic回归分析结果
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Tab 2 Results of univariate and multivariate Logistic regression analysis of bacterial infection in patients with decompensated hepatitis C cirrhosis
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Item | Univariate analysis | Multivariate analysis |
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OR (95%CI) | P value | OR (95%CI) | P value |
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Age≥60 years | 2.045 (1.164‒3.594) | 0.013 | 2.054 (1.104‒3.822) | 0.023 | Gender (female) | 1.569 (1.064‒2.316) | 0.023 | 1.701 (1.112‒2.602) | 0.014 | Diabetes | 1.567 (0.921‒2.666) | 0.098 | ‒ | ‒ | Hypertension | 1.167 (0.709‒1.918) | 0.544 | ‒ | ‒ | Hyperammonemia | 2.002 (1.055‒3.797) | 0.034 | ‒ | ‒ | Ascites | 2.605 (1.789‒3.793) | 0.000 | 2.386 (1.601‒3.557) | 0.000 | History of invasive procedures in the last two weeks① | 2.164 (1.211‒3.867) | 0.009 | 2.605 (1.386‒4.960) | 0.004 | Infusing human serum albumin | 0.357 (0.221‒0.577) | 0.000 | 0.324 (0.194‒0.542) | 0.000 | Laboratory index | | | | | WBC | 1.187 (1.099‒1.282) | 0.000 | ‒ | ‒ | NEUT | 1.239 (1.131‒1.359) | 0.000 | ‒ | ‒ | HGB | 0.995 (0.990‒1.000) | 0.068 | ‒ | ‒ | TP | 0.980 (0.964‒0.997) | 0.018 | ‒ | ‒ | ALB | 0.952 (0.930‒0.975) | 0.000 | ‒ | ‒ | PA | 0.992 (0.988‒0.997) | 0.000 | ‒ | ‒ | TBIL | 1.007 (1.003‒1.010) | 0.000 | ‒ | ‒ | CHOL | 0.680 (0.559‒0.827) | 0.000 | 0.675 (0.549‒0.830) | 0.000 | HDL-C | 0.644 (0.485‒0.854) | 0.002 | ‒ | ‒ | LDL-C | 1.001 (1.000‒1.003) | 0.071 | ‒ | ‒ | CREA | 1.005 (1.001‒1.009) | 0.007 | ‒ | ‒ | IL-6 | 1.001 (1.000‒1.002) | 0.027 | ‒ | ‒ | C1q | 0.995 (0.992‒0.999) | 0.018 | ‒ | ‒ | LDH | 1.001 (1.000‒1.003) | 0.071 | ‒ | ‒ | INR | 1.015 (0.932‒1.107) | 0.727 | ‒ | ‒ | Hospitalization time ≥2 weeks | 1.847 (1.279‒2.677) | 0.001 | 1.629 (1.098‒2.416) | 0.015 |
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