淫羊藿苷对急性肾损伤向慢性肾脏病转化小鼠模型的预防性保护作用

谢林, 程烨, 郑琦敏, 张熙, 付莉莉, 陈敏, 王怡, 梅长林, 谢静远, 顾向晨

Preventive effect of icariin on transition from acute kidney injury to chronic kidney disease in mouse model

XIE Lin, CHENG Ye, ZHENG Qimin, ZHANG Xi, FU Lili, CHEN Min, WANG Yi, MEI Changlin, XIE Jingyuan, GU Xiangchen

图3 AKI-CKD小鼠模型重塑期肾脏的病理损伤以及淫羊藿苷的预防效果 Note： A. Representative images of H-E, PAS and Masson staining kidney sections of AKI-CKD model after 4 weeks (×200). B. Renal tubular injury scores of the three groups after 4 weeks. C. Quantification of Masson trichrome staining after 4 weeks. Scale bar=100 μm. ①P=0.000.

Fig 3 Pathological changes of kidney in the AKI-CKD murine model at remodeling stage and preventive effect of ICA