高脂饮食诱导的小鼠NAFLD模型肝组织中m<sup>6</sup>A甲基化修饰表达谱分析

高脂饮食诱导的小鼠NAFLD模型肝组织中m⁶A甲基化修饰表达谱分析

刘君君, 逯素梅, 张炳杨, 李永清, 马万山

Analysis of m⁶A methylation expression profiles in liver tissue of high-fat diet-induced mouse models of NAFLD

LIU Junjun, LU Sumei, ZHANG Bingyang, LI Yongqing, MA Wanshan

图3 小鼠肝脏mRNA差异m⁶A修饰基因与差异表达基因的联合分析
Note： A. Volcano plot of differential m⁶A methylation mRNAs. B.Cluster diagram showed top 10 differentially m⁶A-methylated mRNAs. C.Four quadrant diagrams showed differential methylation associated with gene expression in the high-fat group and the control group.

Fig 3 Conjoint analysis of differential m⁶A methylation mRNAs and differentially expressed genes in the livers of mice