弥漫大B细胞淋巴瘤患者临床特征及预后分析

赵洁, 姜言, 郝思国

Clinical characteristics and prognosis of patients with diffuse large B-cell lymphoma

ZHAO Jie, JIANG Yan, HAO Siguo

表 3 影响DLBCL患者PFS 的单因素和多因素分析

Tab 3 Univariate and multivariate analysis for the factors affecting PFS of patients with DLBCL

Variable Univariate analysis Multivariate analysis HR (95%CI) P value HR (95%CI) P value Female 0.668 (0.394‒1.132) 0.134 Age>60 years 2.744 (1.553‒4.848) 0.001 2.788 (1.575‒4.936) 0.000 Group B symptoms 1.424 (0.850‒2.386) 0.179 Non-GCB 2.398 (1.243‒4.624) 0.009 2.230 (1.150‒4.324) 0.018 ECOG score ≥2 2.330 (1.379‒3.937) 0.002 Ann Arbor stage Ⅲ‒Ⅳ 2.496 (1.366‒4.561) 0.003 IPI score 3‒5 3.149 (1.722‒5.759) 0.000 Increased LDH [>211 U·L-1] 2.796 (1.413‒5.535) 0.003 2.064 (1.006‒4.234) 0.048 Low albumin [<35 g·L-1] 2.824 (1.657‒4.811) 0.000 2.052 (1.169‒3.602) 0.012 Lymphocytopenia (≤1.1×109·L-1) 2.142 (1.277‒3.592) 0.004 Anemia 1.894 (1.128‒3.179) 0.016 Chemotherapy (R-CHOP) 0.937 (0.400‒2.195) 0.881