弥漫大B细胞淋巴瘤患者临床特征及预后分析

赵洁, 姜言, 郝思国

Clinical characteristics and prognosis of patients with diffuse large B-cell lymphoma

ZHAO Jie, JIANG Yan, HAO Siguo

表4 影响 DLBCL患者OS的单因素和多因素分析

Tab 4 Univariate and multivariate analysis for the factors affecting OS of patients with DLBCL

Variable Univariate analysis Multivariate analysis HR(95%CI) P value HR(95%CI) P value Female 0.586 (0.296‒1.158) 0.124 Age>60 years 2.950 (1.416‒6.145) 0.004 2.269 (1.060‒4.860) 0.035 Group B symptoms 1.283 (0.667‒2.468) 0.455 Non-GCB 1.515 (0.712‒3.223) 0.281 ECOG score ≥2 2.122 (1.092‒4.124) 0.027 Ann Arbor stage Ⅲ‒Ⅳ 2.295 (1.078‒4.888) 0.031 IPI score 3‒5 3.261 (1.484‒7.166) 0.003 2.557 (1.132‒5.778) 0.024 Increased LDH [>211 U·L-1] 3.422 (1.329‒8.808) 0.011 Low albumin [<35 g·L-1] 2.423 (1.238‒4.745) 0.010 Lymphocytopenia (≤1.1×109·L-1) 1.760 (0.911‒3.402) 0.093 Anemia 1.720 (0.891‒3.320) 0.106 Chemotherapy (R-CHOP) 1.422 (0.431‒4.699) 0.563