PTEN对FoxM1可变剪接的调控及该过程在肿瘤细胞迁移中的作用 |
王晓玲, 葛梦凯, 沈少明 |
PTEN-regulated alternative splicing of FoxM1 affects tumor cell migration |
WANG Xiaoling, GE Mengkai, SHEN Shaoming |
图2 FoxM1B和FoxM1C对DU145细胞迁移的影响 Note: A. Western blotting was used to detect the overexpression level of FoxM1B and FoxM1C in DU145 cells. B. Transwell migration analysis results of DU145 cells overexpressing FoxM1B and FoxM1C. Left—typical crystal violet staining photos. Bar=100 μm. Right—statistical analysis of cell migration numbers. C. Wound healing assay of DU145 cells transfected with FoxM1B and FoxM1C overexpression lentivirus. Left—photos of cells incubated for 0 and 24 h in the scratch experiment. Bar=100 μm. Right—statistical analysis of the wound healing rate. |
Fig 2 Effects of FoxM1B and FoxM1C on DU145 migration |