房颤与认知障碍的因果关系:一项孟德尔随机化研究
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高雄, 张秋霞, 杨苗苗, 罗玮, 王月刚, 修建成
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Causal relationship between atrial fibrillation and cognitive impairment: a Mendelian randomization study
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GAO Xiong, ZHANG Qiuxia, YANG Miaomiao, LUO Wei, WANG Yuegang, XIU Jiancheng
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表2 孟德尔分析中结局因素的GWAS信息
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Tab 2 Outcome information of GWAS in the TSMR study
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Analysis | Outcome | ID | Sample size/n | Race | Year | PMID |
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First analysis | Dementia | finn-b-F5_DEMENTIA | 216 771 | European | 2021 | NA | First analysis | Dementia due to Parkinson′s disease | finn-b-PD_DEMENTIA | 216 895 | European | 2021 | NA | First analysis | Vascular dementia | finn-b-F5_VASCDEM | 212 389 | European | 2021 | NA | First analysis | Undefined dementia | finn-b-F5_Dementia_U | 215 511 | European | 2021 | NA | Duplicate analysis | Cognitive performance | ebi-a-GCST006572 | 257 841 | European | 2018 | 30038396 | Duplicate analysis | Alzheimer′s disease | ebi-a-GCST90012877 | 472 868 | European | 2021 | 33589840 | Duplicate analysis | Dementia with Lewy body | ebi-a-GCST90001390 | 6 618 | European | 2021 | 33589841 | Duplicate analysis | Rontotemporal dementia | ieu-b-43 | 3 024 | European | 2010 | 20154673 |
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