基于基因及调控区进化保守性评估细胞和组织发育潜能的定量分析

王志明, 童冉, 杨晨, 焦慧媛, 王一好, 李林颖, 王烨欣, 张丰, 李令杰

Quantitative analysis of the developmental potential of cells and tissues based on evolutionary conservation of genes and regulatory regions

WANG Zhiming, TONG Ran, YANG Chen, JIAO Huiyuan, WANG Yihao, LI Linying, WANG Yexin, ZHANG Feng, LI Lingjie

图3 早期三胚层向相应器官发育过程中细胞特异性超级增强子的鉴定 Note： A. The procedure of SE identifications. B. ChIP-seq signal of H3K27ac in TE regions. C. ChIP-seq signal of H3K27ac in SE regions. D. Biological process of SE-related gene. SE—super enhancer; TE—typical enhancer.

Fig 3 Identification of SEs during the development of three early germ layers to corresponding organs