基于基因及调控区进化保守性评估细胞和组织发育潜能的定量分析

王志明, 童冉, 杨晨, 焦慧媛, 王一好, 李林颖, 王烨欣, 张丰, 李令杰

Quantitative analysis of the developmental potential of cells and tissues based on evolutionary conservation of genes and regulatory regions

WANG Zhiming, TONG Ran, YANG Chen, JIAO Huiyuan, WANG Yihao, LI Linying, WANG Yexin, ZHANG Feng, LI Lingjie

表6 高保守增强子在超级增强子和附近普通增强子中的百分比

Tab 6 Percentages of high-conservation enhancers in SEs and nearby TEs

Tissue type SE/% Nearby SE/% Fold change Ectoderm 3.18 2.83 1.12 Mesoderm 1.04 0.93 1.12 Endoderm 2.32 2.04 1.14 Brain 1.67 1.70 0.98 Skin 0.61 0.66 0.93 Spinal cord 1.60 1.77 0.91 Heart 1.10 0.81 1.36 Muscle 0.42 0.56 0.75 Spleen 0.78 0.92 0.85 Liver 1.35 1.07 1.26 Lung 0.78 1.28 0.61 Pancreas 0.96 0.77 1.25