鲍曼不动杆菌在环境美罗培南浓度变化时耐药性的改变及其机制

赵富茂, 彭玫, 彭晓露, 舒韦韦, 彭丽

Changes in drug resistance of Acinetobacter baumannii during the change of meropenem concentration in the environment and its mechanism

ZHAO Fumao, PENG Mei, PENG Xiaolu, SHU Weiwei, PENG Li

图3 RT-qPCR检测不同耐药性鲍曼不动杆菌菌株中抗MEM相关基因的表达 Note： A. Expression profiles of the genes in ATCC19606 and its MEM-resistant variants. B. Expression profiles of the genes in AB.2014 and its MEM-resistant variants. C. Expression profiles of the genes in ATCC19606-R3 and its MEM-sensitive variants. D. Expression profiles of the genes in AB.2014 and its MEM-sensitive variants. E. Expression profiles of the genes of AB.2014-R1 and its MEM-sensitive variants. ①P=0.005, ②P= 0.003, ③P=0.000, ④P=0.007, ⑤P=0.001, ⑥P=0.002, ⑦P=0.006.

Fig 3 RT-qPCR analysis of MEM-resistance-related genes in A. baumannii strains with different drug resistance