瞬时受体电位香草素1型对高脂饮食诱导的小胶质细胞代谢的调控

沙旭栋, 王晨飞, 鲁佳, 虞志华

Regulation of high-fat diet-induced microglial metabolism by transient receptor potential vanilloid type 1

SHA Xudong, WANG Chenfei, LU Jia, YU Zhihua

图5 Trpv1 敲除可改善高脂饮食诱导的小胶质细胞活化 Note： A/B. Iba-1+ active microglia and GFAP+ reactive astrocytes of WT or TRPV1 KO mice fed on 3-day HFD. Data represent x±s. ?P < 0.05, **P < 0.01, ***P < 0.001, ****P = 0.000. Scale bar: 50 μm.

Fig 5 Genetic Trpv1 deletion ameliorates HFD-induced microglia activation