瞬时受体电位香草素1型对高脂饮食诱导的小胶质细胞代谢的调控

沙旭栋, 王晨飞, 鲁佳, 虞志华

Regulation of high-fat diet-induced microglial metabolism by transient receptor potential vanilloid type 1

SHA Xudong, WANG Chenfei, LU Jia, YU Zhihua

图6 高脂饮食的小鼠大脑内的小胶质细胞和星形胶质细胞激活且上调表达TRPV1 Note： A—C. Co-staining of TRPV1 and Iba1, TRPV1 and GFAP, TRPV1 and NeuN in SCD and 3-day HFD mice. Nuclei were stained in blue with DAPI. Scale bar: 50 μm; Scale bar: 10 μm.

Fig 6 Up-regulation of TRPV1 in active microglia and reactive astrocytes of HFD mice brains