体外膜肺氧合在院内成人心源性休克和心脏骤停中的应用研究
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隋明亮, 汤卫兵, 吴长江, 黄超发, 杨雅迪, 夏大梅
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Application of extracorporeal membrane oxygenation to adults with cardiogenic shock and cardiac arrest in hospital
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SUI Mingliang, TANG Weibing, WU Changjiang, HUANG Chaofa, YANG Yadi, XIA Damei
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表 1 入组患者的一般人口学资料、临床资料及SOFA评分分析
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Tab 1 Analysis of general demographic data， clinical data and SOFA scores of enrolled patients
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| Item | Total (n=19) | E-CS group (n=10) | ECPR group (n=9) |
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| Age/year | 46.5 (34.5, 61.6) | 50.8 (37.2, 63.5) | 43.6 (31.6, 59.8) | | Male/n(%) | 15 (78.9) | 8 (80.0) | 7 (77.8) | | BMI/(kg·m-2) | 22.3±2.4 | 22.5±2.8 | 22.1±1.9 | | Previous underlying diseases/n(%) | | | | | Diabetes | 4 (21.1) | 2 (20.0) | 2 (22.2) | | Hypertension | 5 (26.3) | 4 (40.0) | 1 (11.1) | | Hyperlipidemia | 2 (10.5) | 1 (10.0) | 1 (11.1) | | Chronic heart failure | 3 (15.8) | 1 (10.0) | 2 (22.2) | | Coronary artery disease | 6 (31.6) | 5 (50.0) | 1 (11.1) | | Chronic kidney disease | 3 (15.8) | 2 (20.0) | 1 (11.1) | | Etiology of CS and CA/n(%) | | | | | Acute myocardial infarction | 8 (42.2) | 4 (40.0) | 4 (44.4) | | Acute severe myocarditis | 3 (15.8) | 1 (10.0) | 2 (22.2) | | Heart failure | 7 (36.8) | 4 (40.0) | 3 (33.3) | | Cardiomyopathy | 1 (5.3) | 1 (10.0) | 0 (0) | | Combined IABP treatment/n(%) | 6 (31.6) | 2 (20.0) | 4 (44.4) | | ECMO tube placement time/min | 33.8 (25.5, 44.3) | 38.5 (27.8, 48.2) | 31.5 (25.3, 42.9) | | D to I time/min | 79.5 (45.8, 98.2) | 86.5 (51.3, 116.2) | 76.7 (43.5, 96.9) | | Before ECMO initiation | | | | | Lactic acid level/(mmol·L-1) | 10.7±4.0 | 10.2±4.9 | 11.1±2.8 | | AKI/n(%) | 11 (57.9) | 7 (70.0) | 2 (22.2) | | CRRT/n(%) | 6 (31.6) | 4 (40.0) | 2 (22.2) | | Ventilator support/n(%) | 16 (84.2) | 9 (90.0) | 9 (100.0) | | 24 h LCR after ECMO initiation/% | 67.0 (58.2, 76.3) | 63.6 (49.7, 74.6) | 69.2 (57.5, 83.4) | | Duration of VA-ECMO/d | 4.0 (2.0, 6.8) | 3.9 (2.5, 5.8) | 4.5 (2.6, 6.5) | | ECMO withdrawal success rate/n(%) | 12 (63.2) | 7 (70.0) | 5 (55.6) | | Intensive care duration/d | 11.5 (5.8, 26.2) | 10.2 (3.8, 24.5) | 11.8 (4.1, 28.0) | | Hospital mortality/n(%) | 12 (63.2) | 7 (70.0) | 5 (55.6) | | DDCEW/n(%) | 5 (26.3) | 4 (40.0) | 1 (11.1) | | SOFA scores/score | 14.2±3.7 | 13.8±4.5 | 14.8±4.5 |
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